吳亭穎實驗室 誠徵碩士級研究助理
中央研究院植物暨微生物研究所吳亭穎博士實驗室徵求全職研究助理，該職位將利用系統生物學和預測生物學研究植物與環境之間的交互作用。

The research assistant (RA) in the laboratory of Dr. Ting-Ying Wu at the Institute of Plant and Microbial Biology at Academia Sinica (IPMB, AS) is fully funded. The role will work on the interaction between plants and the environment using systems biology and predictive biology.

RA 負責產生次世代定序資料集，包括批量 RNA 定序、ATAC-seq、DAP-seq、單細胞 RNA 定序和單核 ATAC-seq。

The RA is responsible for generating datasets for next-generation sequencing, including bulk RNA sequencing, ATAC-seq, DAP-seq, single-cell RNA sequencing, and single-nuclei ATAC-seq.

此工作將負責次世代定序的樣本庫以及數據集之製備，包括bulk RNA-seq、ATAC-seq、DAP-seq、single-cell RNA-seq和single-nuclei ATAC-seq。

The research assistant (RA) in the laboratory of Dr. Ting-Ying Wu at the Institute of Plant and Microbial Biology at Academia Sinica (IPMB, AS) is fully funded. The role will work on the interaction between plants and the environment using systems biology and predictive biology.

吳實驗室是 IPMB 的一部分，該實驗室由來自台灣和其他 15 個以上國家的近 300 名研究人員和工作人員組成。 它位於台灣台北的 AS 主校區。 AS 提供最先進的核心設施，包括細胞生物學、顯微鏡、高效能運算和 OMIC 設施，支援我們追求尖端研究。 我們的主要目標是在實驗室成員之間培養高度跨學科和協作的氛圍。 欲了解更多信息，請訪問吳實驗室網站。

The Wu Lab is a part of the IPMB, which comprises nearly 300 researchers and staff members from Taiwan and over 15 other countries. It is located on the main campus of AS in Taipei, Taiwan. AS provides state-of-the-art core facilities, including those for cell biology, microscopy, high-performance computing, and OMICs, which support our pursuit of cutting-edge research. Our primary goal is to cultivate a highly interdisciplinary and collaborative atmosphere among lab members. For more information, please visit the Wu Lab website.

參與微生物發育的跨領域研究。你會參與下列兩個主題之一：
Interdisciplinary research on the development of microbial systems. You will be involved in either of the following projects.

研究主題一：研究不同種類的酵母菌如何利用「反應擴散系統」，調控細胞內極性蛋白在時間和空間上的的動態分佈。這些極性蛋白在細胞內的分佈決定了細胞的極性，最終決定了細胞以哪個模式生長。

Topic 1: To elucidate the spatial temporal dynamics of the polarity proteins within single yeast cells using reaction-diffusion systems. How these polarity proteins distribute determines cell polarity modes and ultimately the growth modes of a single cell.

研究主題二：細菌不僅僅是以單細胞形式生長，也能形成多細胞的群落，稱作生物膜。生物膜的發育就如同多細胞胚胎發育一般，仰賴細胞依照特定紋路分化。我們在研究生物膜內各個單一細胞的分子時鐘，如何彼此溝通耦合，進而形成同步的紋路。
Topic 2: Bacteria are not exclusively single cell organisms. Rather, they form multicellular communities called biofilms. Biofilms develop using patterned cell differentiation, similar to embryogenesis. This project aims to elucidate how oscillators within individual bacteria couple with each other to form synchronized patterns collectively in a biofilm.

這兩個跨領域主題都牽涉到動態系統理論和分子細胞生物兩大領域間的對話。我們希望找到的人要至少在其中一個領域有完整的基礎知識及研究經驗，且願意與另一個領域的人討論與密切合作。取決於你過去受過的訓練，你的工作內容可能主要會是分子細胞生物學實驗與光學顯微鏡操作，或者是數學分析以及微分方程系統的模擬。

Both of these topics heavily rely on the crosstalk between Dynamic Systems Theory and Molecular Cell Biology. We are looking for people who are well-trained in one of these two fields and willing to work closely with a partner trained in the other field. Depending on your expertise, your responsibilities will be either predominantly Molecular genetics plus Live cell microscopy, or Mathematical analysis and simulations of differential systems.