實驗室網站：https://sites.google.com/view/kock-lab/home

1. A PhD degree in Plant Biology/Genetics/Biochemistry or a related discipline.
2. A good command of English and capable of acquiring new skills.
3. Must be experienced in more than one of the following techniques: (1) molecular biology (Golden gate/gateway/Gibson assembly), confocal microscopy (time-lapse imaging, image analysis), DNA sequencing analysis (RNAseq, scRNAseq), Biomolecular interactions (in vitro pull-down, MicroScale Thermophoresis, Isothermal titration calorimetry).

A good track record of publication that demonstrates the above.

本實驗室利用蘚苔為實驗材料，致力於研究陸生植物的外表形態環境適應及其訊號傳遞的演化過程機制。本計畫會用到分子生物、遺傳、基因組編輯、顯微鏡觀察及蛋白純化等技術。本實驗室老師具有高度教學熱忱，歡迎對植物研究工作有熱忱的你加入。The lab is using moss (Physcomitrium patens) as a model to investigate various developmental biology-related questions in plants. The lab routinely employs techniques such as genetic manipulations, protein expression/purification, and confocal microscopy observation. We encourage those interested in plant biology to be part of the team. 實驗室網站：https://sites.google.com/view/kock-lab/home

（1）具備並熟悉以下其中一項技術：Molecular biology (Golden gate/gateway/Gibson assembly), confocal microscopy (time-lapse imaging, image analysis), DNA sequencing analysis (RNAseq, scRNAseq), Biomolecular interactions (in vitro pull-down, MicroScale Thermophoresis, Isothermal titration calorimetry).

（2）中英文能力佳（實驗室會議及實驗紀錄皆使用英文）A  good command of English and Mandarin；

（3）生命科學等相關學位 Possess a life science-related degree in the fields of plant and/cell biology/genetics ；

（4）外籍人士也歡迎。International applicants are encouraged to apply.

The major research interests in the LAI lab are to understand the molecular mechanisms underlying how bacterial pathogens deploy protein secretion systems for survival at its ecological niche and successful infection inside the plant host. We study the mechanistic and biological insights of the two major protein secretion nanomachines, type IV and type VI secretion systems (T4SS and T6SS), in Agrobacterium tumefaciens, the causal agent of crown gall disease and powerful gene transfer tool. We also aim to identify novel agrobacterial and plant genes critical for plant transformation and gene editing. The knowledge may provide new insights to improve Agrobacterium-mediated plant transformation and translational applications in biomedicine and/or agriculture.

The postdoc will carry out a 3-year NSTC grant to study the molecular mechanisms of T6SS offense and defense with focuses to investigate how the recipient cell factors involved in regulating the toxicity of T6SS antibacterial effector.

The LAI lab provides the research environments and expertise on studies of protein secretion and pathogen-plant interactions using various tools including genetics/genomics, molecular biology, biochemistry/proteomics, and cell biology. The research may expand to study structural aspects of effector-associated complex using X-ray crystallography and cryoEM through collaborations with the assistance of Academia Sinica Protein Clinic and Cryo-EM Center. The postdoc is also encouraged to develop an independent project and will be trained to serve as a mentor toward an independent investigator. The LAI lab is also active in international collaborations, which will bring opportunities for abroad training.