[Ming-Hsiun Hsieh] Plant ACR proteins diversified in conjunction with the water-to-land transition

Liao <em>et al</em>., 2020, <em>Amino Acids</em>

Fig. 1 Land-plant ACR proteins form three distinct clades highlighted in pink, green, and blue. Algal ACRs fall outside the distinct clades of land-plant ACRs.

Dr. Ming-Hsiun Hsieh’s laboratory reported that plant ACR (ACT domain repeat) proteins comprise three groups based on domain composition and sequence (Fig. 1). Group III ACRs, which are conserved from algae to land plants, may represent the first ACRs that evolved in the plant kingdom. By contrast, the emergence of group I and II ACRs seems to coincide with the appearance of land plants. These ACT-domain-containing proteins may have evolved from the regulatory modules of more ancient amino acid metabolic enzymes. The paper is published in Amino Acids (https://link.springer.com/article/10.1007/s00726-020-02844-1) by Hong-Sheng Liao, Yi-Hsin Chung and Camille Chardin of the Hsieh Lab.