[Nakamura Lab] Phosphatases in membrane lipid remodeling under phosphate starvation

PECP1 and PS2 belong to an emerging class of phosphatase induced by phosphate starvation and dephosphorylates phosphocholine and phosphoethanolamine in vivo. A research project led by Dr. Yuki Nakamura reported detailed spatiotemporal expression pattern of PECP1 and PS2 in response to phosphate starvation. Characterization of PECP1 and PS2 suggest that they are ER-localized phosphatases that show similar expression pattern yet have a distinct substrate specificity in vivo.

Link: https://www.frontiersin.org/articles/10.3389/fpls.2019.00662/abstract